Absence of MALT1 translocations in primary cutaneous marginal zone B-cell lymphoma.
نویسندگان
چکیده
The implication of MALT1 gene in the pathogenesis of primary cutaneous marginal zone B-cell lymphomas (PCMZL) has been a matter of controversy. We examined the presence of MALT1 translocations in a series of 23 PCMZL. FISH assay with a MALT1 dual color break apart translocation probe revealed the absence of MALT1 translocations in all cases.
منابع مشابه
Primary cutaneous marginal zone B-cell lymphoma.
Primary cutaneous marginal zone B-cell lymphoma (PCMZL) is included as one of the major types of primary cutaneous B-cell lymphoma in the revised World Health Organization-European Organization for Research and Treatment of Cancer classification. Clinically, PCMZL is an indolent disease and has an excellent prognosis. PCMZL is composed of a polymorphous infiltrate that includes centrocyte-like,...
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عنوان ژورنال:
- Haematologica
دوره 89 9 شماره
صفحات -
تاریخ انتشار 2004